Health & Fitness

The Peptide Lab

Dave Huffman

The Peptide Lab explores the rapidly evolving world of peptides, metabolic health, body composition, recovery, longevity, performance, and healthy aging. Each episode takes a peptide, therapy, claim, or emerging area of research and puts it in the lab. What is it? How is it believed to work? What does the research actually show? What are people claiming it can do? Where is the evidence strong, where is it preliminary, and where does the hype get ahead of the science? From GLP-1 medications and metabolic health to growth-hormone pathways, recovery research, mitochondrial biology, sleep, body composition, and longevity science, The Peptide Lab translates complicated subjects into conversations ordinary people can understand. No miracle claims. No pretending experimental research is settled science. Just curiosity, evidence, intelligent discussion, and better questions. When the claims get complicated, take it to the lab.

4 episodes

The Mitochondrial Peptide Connection: MOTS-c, Humanin, and Cellular Energy 5 Oct 2026 · 7 min Mitochondria are often called the powerhouses of our cells, but they also produce their own set of signaling peptides—MOTS-c and humanin—that may influence metabolism, exercise re…

The Sleep-Metabolism Peptide Axis: How Melatonin, Ghrelin, and Cortisol Shape Your Health 4 Oct 2026 · 11 min Sleep is more than a nightly reset. It is a biological command center where peptides like melatonin, ghrelin, and cortisol orchestrate hunger, metabolism, and recovery. In this ep…

The Muscle-Sparing GLP-1 Question: Can We Lose Fat Without Sacrificing Lean Mass? 3 Oct 2026 · 11 min GLP-1 medications like semaglutide have transformed weight management, but a critical question is emerging: as the scale drops, how much of that weight is fat versus muscle? This…

Creatine vs. Collagen: What the Science Really Says About Muscle, Skin, and Aging 2 Oct 2026 · 10 min Creatine and collagen are everywhere: in powders, gummies, social media ads, and coffee shop add-ins. But do these popular peptides actually do what people claim? In this episode,…